Microscale Life Sciences Center - An NIH Center of Excellence in Genomic Science (CEGS)

ARIZONA STATE UNIVERSITY (ASU)
TEMPE, ARIZONA

Name Details
Deirdre Meldrum, Ph.D.
ASU: Principle Investigator and Professor.
Electrical engineer leading the collaborative CEGS Microscale Life Sciences Center. Directs projects applying microfluidic device technologies to address questions related to esophageal cancer and inflammation.
Mark Holl, Ph.D.
ASU: Research Scientist
Systems engineer coordinating lab-on-chip design and implementation.
Yanqing Tian, Ph.D.
ASU: Research Assistant Professor
Synthetic chemist designing highly-sensitive and specific optical probes and sensor systems for physiologically-relevant analytes.
Laimonas Kelbauskas, Ph.D.
ASU: Research Assistant Professor
Biophysicist leading projects applying microfluidic device and single-cell transcriptomics technologies to elucidate effects of intercellular communication on gene expression.
Nanna Hansen, M.S.
ASU: Associate Research Technologist
Cell culture and biology expert working on single-cell metabolic analyses.
Honor Glenn, Ph.D.
ASU: Associate Research Scientist
Cell biologist and confocal microscopist performing live- and immunostained cell experiments.
Thai Tran, Ph.D.
ASU: Postdoctoral Fellow.
Maintains primary cell cultures from esophageal biopsies and analyzes cell population heterogeneity.
Weimin Gao, Ph.D.
ASU: Associate Research Scientist
Molecular biologist performing few- and single-cell transcriptomics analyses.
Joseph Chao, Ph.D.
ASU: Research Assistant Professor.
Mechanical engineer working on low-cost, high-throughput technologies for single-and few-cell culture and analysis.
Kimberly Bussey, Ph.D.
ASU, TGen: Cancer cytogeneticist.
Providing guidance in experimental designs and data analysis.
Fengyu Su, Ph.D.
ASU: Associate Research Scientist
Polymer chemist developing sensors for single-cell physiological analysis.
Patti Senechal, M.S.
ASU: Research Technologist
Responsible for cell and tissue culture.
Jeff Houkal, B.S.
ASU: Mechanical Engineer
Responsible for designing microfluidic and optical analysis instrumentation.
Juan Vela
ASU: Assistant Research Technologist
Machinist building microfluidic and optical analysis instrumentation.
Dean Smith
ASU: Software Engineer
Building integrated environment for instrument control and data acquisition.
Cliff Anderson, M.S.
ASU: Research Scientist
Systems engineer leading high-throughput cell analysis device development projects.
Roger Johnson, Ph.D.
ASU: Research Scientist and Lab Manager
Investigator. Project coordinator and bioengineer performing imaging experiments.
Craig Reading
ASU: Associate Research Technologist
Biologist performing experiments and data analysis
Kristen Lee
ASU: Assistant Research Technologist
Biologist performing experiments and data analysis.
Hong Wang Ph.D
ASU: Associate Research Scientist
Biomedical engineer designing and implementing microfabrication processes.
Jia Zeng
ASU: Ph.D Candidate
Biological Design Graduate Program.
Benjamin Ueberroth
Biologist performing experiments and data analysis.

UNIVERSITY OF WASHINGTON (UW)
SEATTLE, WASHINGTON

Name Details
Brad Cookson, M.D., Ph.D.
UW: Co-PI and Professor
Molecular biologist and pathologist leading experimental program on pyroptosis.
Alex Jen, Ph.D.
UW: Co-PI and Professor
Chemist leading development of novel micro-optical sensors.
Lloyd Burgess, Ph.D.
UW: Co-PI and Professor
Analytical chemist leading experimental program on optical analysis of single cells.
Lisa Petersen
UW: Director, UW GenOM Project, College of Engineering
Wendy Loomis, Ph.D.
UW: Research Scientist
Designing experiments to address the relationships between host cell heterogeneity and the pathway, kinetics and biochemistry of cell death, including pyroptosis and apoptosis, after stimulation by infectious agents.
Sei-Hum Jiang, Ph.D.
UW: Chemist
Performing experiments with micro-optical biosensors.
Michael Konopka, Ph.D.
UW: Postdoctoral fellow
Biophysicist performing bulk and single cell experiments on Barrett's esophageal epithelial cells.

FRED HUTCHINSON CANCER RESEARCH CENTER (FHCRC)
SEATTLE, WASHINGTON

Name Details
Brian Reid, M.D., Ph.D.
FHCRC: Co-PI and Professor
Gastroenterologist and geneticist leading experiments on genomic instability in esophageal adenocarcinoma.
Thomas Paulson, Ph.D.
FHCRC: Staff Scientist
Designing and conducting experiments to determine the effects of hypoxia on Barrett’s esophageal epithelial cells.

BRANDEIS UNIVERSITY
WALTHAM, MASSACHUSSETTS

Name Details
Lawrence J. Wangh, Ph.D.
Brandeis: Co-PI and Professor
Director of the Laboratory for Molecular Diagnostics and Global Health, co-inventor of LATE-PCR and its allied technologies.
J. Aquiles Sanchez, Ph.D.
Brandeis: Senior Research Scientist
Leader of Oncology Team, and co-Inventor of LATE-PCR and its allied technologies
Within MLSC, applying these technologies to analysis of mitochondrial genome variation in Barrett’s esophagus cell.
Yanwei Jia, Ph.D.
Brandeis: Research Scientist
Co-Inventor of LATE-PCR and its allied technologies
Within MLSC, applying these technologies to analysis of gene expression in single cells, as well as construction of microfluidics devices.
Adam Osborne, Ph.D.
Brandeis: Post-doctoral fellow
Co-Inventor of LATE-PCR and its allied technologies.
Within MLSC, using these technologies to construct multiplexed LATE-PCR assays for analysis of mitochondrial genomes at the single molecule level. These assays are used to measure increases in mutations following treatment of cultured cells and animals with drugs and chemicals.