Microscale Life Sciences Center - An NIH Center of Excellence in Genomic Science (CEGS)

Reid, Fred Hutchinson Cancer Research Center

The Reid lab focuses on clonal evolution, cancer prevention and cancer risk prediction in Barrett's esophagus.

Director: Brian J. Reid, MD, PhD

Brian J Reid M.D., Ph.D. is the Head of the Seattle Barrett's Esophagus Program. As an undergraduate and graduate student in Genetics, he discovered yeast cell cycle mutations and participated in developing the first genetic model of eukaryotic cell division. After graduate school, he entered medical school to study neoplastic evolution with the goal of improving care for patients who are at risk for or have cancer. He became a gastroenterologist and he has been investigating Barrett's esophagus since 1983. The goal of Dr. Reid's work on Barrett's esophagus is to understand the mechanisms by which environmental exposures (i.e. chronic reflux ; aspirin or other nonsteroidal antiinflammatory agents) affect the evolution of clones that leading to the development of esophageal adenocarcinoma in patients with Barrett's esophagus. This understanding can then be used to develop interventions to prevent progression to cancer or to detect the cancers and premalignant abnormalities when they are early and curable.